Japan's Nikkei 225 stock average gained 0.9 per cent to 15,274.07 while South Korea's Kospi inched down 0.1 per cent to 1,974.68. Australia's S&P/ASX 200 rose 0.3 per cent to 5,462.20.
European markets opened mostly down. Britain's FTSE 100 fell 0.2 per cent to 4,410.34 and Germany's DAX was down 0.7 per cent to 9,475.37. The CAC 40 in Paris shed 0.2 per cent to 4,410.34.
Wall Street was poised for an uninspiring open, with Dow Jones and S&P 500 futures both little changed ahead of the February employment report due out later Friday. The payrolls data often set the market mood for a week or two.
Investors had been encouraged by a pause in the escalation of tensions in the Ukraine and by a meeting of China's top legislative body which pledged to advance Communist Party plans for promoting market forces and domestic consumption in Asia's economic engine.
However, a wait-and-see approach appeared to take hold ahead of Friday's release of the U.S. employment report. China is also expected to release trade and inflation data on the weekend.
China's Shanghai Composite Index fell 0.1 per cent to 2,154.35 and Taiwan's benchmark was flat at 8,713.96. Hong Kong's Hang Seng fell 0.2 per cent to 22,660.49.
Benchmark crude for April delivery was up 26 cents to $101.82 a barrel in electronic trading on the New York Mercantile Exchange. The contract rose 11 cents to $101.56 on Thursday.
In currencies, the dollar weakened to 102.85 Japanese yen from 103.07 yen late Thursday. The euro rose to $1.3871 from $1.3866.